Health

An aspirin a day does not keep dementia at bay

ANI | March 26, 2020 10:11 AM
Representative image

Washington D.C. [USA], Mar 26 (ANI): In a recent study, researchers have found that taking a low-dose aspirin once a day does not reduce the risk of thinking and memory problems caused by mild cognitive impairment or probable Alzheimer's disease, nor does it slow the rate of cognitive decline.

The study was published in the online issue of Neurology®, the medical journal of the American Academy of Neurology.

Aspirin has anti-inflammatory properties and also thins the blood. For years, doctors have been prescribing low-dose aspirin for some people to reduce their risk of heart disease and stroke. However, there are also possible risks to taking aspirin, including bleeding in the brain, so guidance from a doctor is important.

Because aspirin can be beneficial to the heart, researchers have hypothesized, and smaller previous studies have suggested, that it may also be beneficial to the brain, possibly reducing the risk of dementia by reducing inflammation, minimizing small clots or by preventing the narrowing of blood vessels within the brain.

"Worldwide, an estimated 50 million people have some form of dementia, a number that is expected to grow as the population increases, so the scientific community is eager to find a low-cost treatment that may reduce a person's risk," said study author Joanne Ryan, PhD, of Monash University's School of Public Health in Melbourne, Australia. "Unfortunately, our large study found that a daily low-dose aspirin provided no benefit to studying participants at either preventing dementia or slowing cognitive decline."

The study involved 19,114 people who did not have dementia or heart disease. A majority of participants were age 70 or older. They took thinking and memory tests at the start of the study as well as during follow-up visits.

Half of the people were given daily 100-milligram low-dose aspirin while the other half were given a daily placebo. They were followed for an average of 4.7 years, with annual in-person examinations.

Over the course of the study, 575 people developed dementia.

Researchers found no difference between those who took aspirin and those who took a placebo in the risk of developing mild cognitive impairment, dementia, or probable Alzheimer's disease. There was also no difference in the rate of cognitive change over time.

"While these results are disappointing, it is possible that the length of just under five years for our study was not long enough to show possible benefits from aspirin, so we will continue to examine its potential longer-term effects by following up with study participants in the coming years," said Ryan.

A limitation of the study was that only relatively healthy people were enrolled, and such a population may benefit less from aspirin than the general population. (ANI)

Have something to say? Post your comment
Must Read
Punjab villages show the way to combatting COVID-19 with self isolation
Punjab villages show the way to combatting COVID-19 with self isolation
Novel Coronavirus (COVID-19):  Ex-commandant donates Rs 5 lakh out of his pension account for Punjab Chief Minister relief fund
Novel Coronavirus (COVID-19): Ex-commandant donates Rs 5 lakh out of his pension account for Punjab Chief Minister relief fund
DC and CP for transforming ‘self home quarantine’, ‘social distancing’ and ‘Theekari Pehras’ into a mass movement
DC and CP for transforming ‘self home quarantine’, ‘social distancing’ and ‘Theekari Pehras’ into a mass movement
Punjab sets up transport control rooms to ensure smooth movement of essentials
Punjab sets up transport control rooms to ensure smooth movement of essentials
One more Corona Positive patient dies in Punjab
One more Corona Positive patient dies in Punjab
Administration pulls up socks for smooth and hassle free procurement of wheat from April 15
Administration pulls up socks for smooth and hassle free procurement of wheat from April 15
Lockdown : Radha Soami Satsang Beas prepares 'langar' for needy in Punjab, other states
Lockdown : Radha Soami Satsang Beas prepares 'langar' for needy in Punjab, other states
Technical Education Board to give Rs 5 crore in CM's relief fund: Channi
Technical Education Board to give Rs 5 crore in CM's relief fund: Channi
MP, MLAs, DC, CP and SSP join heads for further expediting distribution of relief material to the needy and underprivileged sections of society
MP, MLAs, DC, CP and SSP join heads for further expediting distribution of relief material to the needy and underprivileged sections of society
The Department of Consumer Affairs will issue daily list of essential commodities during lockdown
The Department of Consumer Affairs will issue daily list of essential commodities during lockdown
DC and SSP leads flag march in Nakodar Sub-Division
DC and SSP leads flag march in Nakodar Sub-Division
Capt Amarinder directs DGP to finalise security plan for smooth procurement
Capt Amarinder directs DGP to finalise security plan for smooth procurement