Health

Over 6,000 antibiotic resistance genes in gut bacteria identified

Agency | December 02, 2018 01:17 PM

LONDON:  Researchers have identified over 6,000 antibiotic resistance genes found in bacteria that inhabit the human gut, which is home to trillions of micro-organisms, mainly bacteria.

"Most gut bacteria live in a harmless relationship with the human host. However, the gut is also home to bacteria that can cause infections in hospitalised patients," said one of the researchers Willem van Schaik, Professor at the University of Birmingham.

"Unfortunately, these bacteria are becoming increasingly resistant to antibiotics and we need to understand the processes that contribute to this development," he added.

To identify resistance genes in gut bacteria, team of researchers, led by the Institut National de la Recherche Agronomique (INRA) in France, developed a new method by comparing the three-dimensional structures of known antibiotic resistance enzymes to the proteins that are produced by gut bacteria.

They then applied this method to a catalogue of several million genes of the gut, leading to the identification of over 6,000 antibiotic resistance genes that are very different from previously identified genes in pathogenic bacteria, according to the study published in the journal Nature Microbiology.

"Most of these genes appeared to be present in bacteria that live in a harmless relationship with the human host, so may not be an immediate threat to human health," van Schaik said.

"However, the continuing use of antibiotics may lead to these resistance genes being transferred to pathogenic bacteria, thereby further reducing the effectiveness of antibiotics in treating infections," he added.

Have something to say? Post your comment
Must Read
Smuggling through border cannot be fully stopped, says BGB
Smuggling through border cannot be fully stopped, says BGB
'Batla House': Nora Fatehi steals the show with recreated version of 'O Saki Saki'
'Batla House': Nora Fatehi steals the show with recreated version of 'O Saki Saki'
Kumar Keshav, the man behind success of Lucknow Metro
Kumar Keshav, the man behind success of Lucknow Metro
 DC Exhorts students to be Ambassadors of conserving the water table in District by participating Zealously in ‘Jal Shakti Abhiyan’
DC Exhorts students to be Ambassadors of conserving the water table in District by participating Zealously in ‘Jal Shakti Abhiyan’
Nutritious and Delicious Kiwifruit from Chile makes deeper inroads into Indian Market
Nutritious and Delicious Kiwifruit from Chile makes deeper inroads into Indian Market
Defence Min issues Rs 2000 cr tender for critical heavyweight torpedoes for submarines
Defence Min issues Rs 2000 cr tender for critical heavyweight torpedoes for submarines
I will come to India in another 24 hours: IMA founder Mansoor Khan
I will come to India in another 24 hours: IMA founder Mansoor Khan
Maharani The Kitchen offers you the Best Royal Cuisine in Delhi/NCR
Maharani The Kitchen offers you the Best Royal Cuisine in Delhi/NCR
Rohit Sharma feels cricket rules need 'serious look in'
Rohit Sharma feels cricket rules need 'serious look in'
I'm not a perfect role model, says Neymar
I'm not a perfect role model, says Neymar
No proposal under govt's consideration for special category status to Odisha: Anurag Thakur
No proposal under govt's consideration for special category status to Odisha: Anurag Thakur
Pro-Khalistani leaders continue to hold key positions in PSGPC
Pro-Khalistani leaders continue to hold key positions in PSGPC